CUSTOM SERVICES | NO SUCCESS, NO CHARGE

Your research, in 3D. Custom organoid models built around your science.

abm helps researchers move from concept to validated, characterization-ready organoid models with feasibility-first support and project-specific workflow development.

Building a physiologically relevant organoid model can be technically demanding. Our custom organoid generation service supports feasibility assessment, workflow design, culture optimization, and optional downstream characterization.

From iPSC- and ESC-derived models to tissue-derived (TDO) and patient-derived tumor organoids (PDO), abm supports the full range of organoid development — each project scoped to your starting material, biology, and downstream assay requirements.

HOW IT WORKS

A project-based process built around you

Organoid development depends on the right cell source, culture conditions, and downstream assay goals. This workflow keeps each project grounded in feasibility, optimization, and clear deliverables.

Step 01

Project inquiry & feasibility

Share your research goals so we can assess source material suitability, culture complexity, logistics, and project scope before moving forward.

  • Research goal alignment
  • Starting material or cell source review
  • Culture complexity and logistics assessment
Step 02

Workflow design

We co-develop a project-specific plan covering matrix conditions, media formulation, growth factors, culture format, milestones, and deliverables.

  • Matrix and media condition planning
  • Growth factor and supplement strategy
  • Culture format matched to downstream goals
Step 03

Culture & optimization

Organoids are established, expanded, and iteratively optimized with morphology monitoring and documentation throughout development.

  • Organoid initiation, establishment, and expansion
  • Condition optimization across defined parameters
  • Morphology monitoring and progress documentation
Step 04

Delivery & characterization

Validated models are delivered with optional downstream characterization and a feasibility review to support your next assay.

  • Validated, quality-controlled organoid models
  • Feasibility review for assay integration
  • Optional services - toxicity testing, identification testing, functional testing
TISSUE TYPES & APPLICATIONS

Broad model scope across organ systems

abm evaluates each project individually and supports organoid development across a wide range of tissue origins and disease applications.

01

Kidney / Renal

Custom models for kidney-focused development and disease research.

02

Brain / Neural

3D culture support for neural and brain-related research questions.

03

Lung / Pulmonary

Organoid workflows for lung biology and respiratory disease applications.

04

Heart / Cardiac

Project-specific planning for cardiac model development and optimization.

05

Tumour / Patient-Derived

Feasibility review for tumour and patient-derived organoid projects.

06

Intestinal / Colorectal

Support for intestinal and colorectal organoid establishment and expansion.

Not sure if your model type is supported?

Submit a feasibility inquiry. We review source material, organoid type, project complexity, characterization needs, and shipping feasibility before confirming scope.

MODELS OFFERED

Organoid model options for custom development

From stem cell-derived systems to tissue- and patient-derived models, each project is scoped around your source material, species, and delivery requirements.

Service category Description Species Delivery format
iPSC / ESC-derived organoids Stem cell-derived organoids generated from validated iPSC, ESC, or other pluripotent stem cell lines.
Human Only
Live Only
Tissue-derived organoids (TDO) Organoids generated from fresh normal tissue, biopsy, or isolated adult stem/progenitor cells.
MouseHuman
Frozen
Patient-derived organoids (PDO) Organoids generated from patient tumor tissue, biopsy, surgical specimen, malignant ascites, pleural effusion, or existing PDO culture.
MouseHuman
Frozen

Shipping note: For iPSC/ESC-derived organoids, shipment is live only in transport medium. All PDO-related orders are shipped frozen.

OPTIONAL SERVICES

Additional testing to support downstream applications

Optional testing services can be added to support model validation, assay planning, and application-specific study goals.

Toxicity Testing

Evaluate the response of organoids to compounds, biologics, or environmental agents to assess potential cytotoxic effects and overall tissue health.

ID

Identification Testing

Confirm organoid identity and differentiation status using validated molecular and cellular markers relevant to the target tissue type.

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Functional Testing

Assess the biological activity and physiological performance of organoids through tissue-specific functional assays.

REPRESENTATIVE ORGANOID MODELS

Morphology and characterization examples

Representative organoid images showing model morphology, culture progress, and optional downstream characterization outputs across different tissue and disease contexts.

Heart organoid morphology example

Heart Organoid

Representative brightfield image showing heart organoid morphology in 3D culture.

Kidney organoid EPCAM staining example

Kidney Organoid

Representative immunofluorescent image demonstrating kidney organoid characterization.

Midbrain organoid morphology example

Midbrain Organoid

Representative brightfield image showing midbrain organoid morphology in 3D culture.

Mouse small intestine organoid example

Intestinal Organoid

Representative brightfield image showing intestinal organoid morphology in 3D culture.

TNBC tumour organoid model example

Tumor Organoid

Representative brightfield image showing triple negative breast cancer organoid morphology.

Patient-derived tumour organoid example

Patient Derived Organoid

Representative brightfield image of patient derived tumor organoid in 3D culture.

EVERY PROJECT INCLUDES

Comprehensive support from start to finish

Each engagement is designed to reduce technical uncertainty and keep your model development aligned with downstream research needs.

Source suitability evaluation

Review of starting material or cell source suitability before committing scope.

Workflow development

Project-specific reporting and workflow development around culture requirements.

3D culture optimization

Condition, matrix, and media optimization to support model establishment.

Culture initiation and expansion

Organoid culture initiation, establishment, expansion, and monitoring.

Morphology documentation

Progress documentation to track culture behaviour and development.

Downstream feasibility

Assessment for downstream applications and next-step assay planning.

Integrated reagent expertise

Access to abm’s broader cell biology, reagent, and assay support ecosystem.

WHY abm

Purpose-built for every stage of drug discovery and disease research

Most organoid services are designed for high-throughput screening. abm supports researchers who need a model that may not exist yet.

20+ years in Cell Biology
1000+ Cell Lines Available
100+ Cell Types Supported

One-on-one project support

Dedicated expert support from inquiry through delivery, with direct communication throughout the project.

Flexible Source Materials

Projects are evaluated based on your starting material, whether that's a commercial cell line, primary tissue, iPSC-derived cells, or patient-derived samples.

Integrated cell biology expertise

abm develops and manufactures supporting media, supplements, and culture formats for a more connected workflow.

Characterization Capabilities

Optional qPCR, IHC, and immunofluorescence outputs are available to validate your model and bridge development with downstream experimental use.

Experimentally validated organoid models

Optional downstream characterization helps bridge model development with experimental use.

Organoid development expertise

Depth across renal, neural, pulmonary, cardiac, tumour, and intestinal model types — with protocol experience to support novel and established systems alike.

FAQ

Frequently asked questions

Common questions about custom organoid generation, starting materials, timelines, downstream applications, and project support.

What types of organoids can abm generate as part of this service?

abm supports custom organoid development across renal, neural, pulmonary, cardiac, intestinal, and tumour/patient-derived model types. Each project is evaluated individually, so if your tissue type isn't listed, submit a feasibility inquiry and we'll assess suitability before confirming scope.

What starting materials can I use for a custom organoid project?

We work with a range of source materials including commercial cell lines, primary tissue samples, iPSC-derived cells, and patient-derived samples. Suitability is reviewed during the feasibility stage before any project commitment is made.

How long does a custom organoid generation project typically take?

Timelines vary based on organoid type, source material complexity, and downstream characterization requirements. After your inquiry is submitted, our team will provide a project-specific timeline as part of the feasibility and workflow design phase.

Can organoid models generated through this service be used for drug screening?

Yes. Organoid models developed through abm's service are suitable for drug screening, toxicity testing, and compound efficacy studies. Each model is optimized and characterized to ensure it meets the quality and reproducibility standards required for downstream assay use.

Do I need to have prior organoid experience to use this service?

No prior organoid experience is required. abm's feasibility-first approach is designed to support researchers at any stage — whether you're establishing your first 3D model or optimizing an existing system. Our team works with you from inquiry through delivery to ensure the project is set up for success.

Start your organoid project

Tell us about your research goals and we’ll assess feasibility together. There is no commitment required to inquire.

PROJECT INQUIRY

Submit your organoid services project form

Tell us about your research goals, starting material, desired model type, and downstream assay needs. Our team will review feasibility and available support options.