Engineered extracellular matrix and surface modification solutions that recapitulate native tissue microenvironments, improving attachment, proliferation, and differentiation for primary cells, stem cells, and 3D culture models.
abm’s ready-to-use coating solutions help create a more biologically relevant culture surface for reliable cell attachment, morphology, and downstream performance.
Culture surface chemistry can directly influence cell attachment, morphology, survival, and differentiation outcomes. The right coating helps bridge the gap between plasticware and a more physiologically relevant extracellular matrix environment.
Coating surfaces with ECM proteins or synthetic polymers provides the integrin-binding ligands cells need to anchor, spread, and survive. Uncoated plastic is often insufficient for primary and sensitive cell types.
Substrate composition and stiffness influence cell fate decisions. Selecting the right coating can drive more physiologically relevant differentiation and help maintain cell phenotype over extended culture.
Hydrogel and basement membrane matrix coatings enable 3D spheroid formation and organoid culture by providing structural scaffolding that mimics native tissue architecture.
Support 3D culture, organoid formation, primary cell adhesion, and demanding adherent cell workflows with ready-to-use ECM-based solutions.
A basement membrane-like hydrogel matrix that supports 3D cell culture, organoid formation, and tumour spheroid growth. Provides structural scaffolding with native ECM complexity including laminin, collagen IV, and heparan sulfate proteoglycans.
A comprehensive extracellular matrix preparation that provides a biologically complex substrate for demanding cell types. Promotes robust adhesion and maintains cell morphology for primary cells, epithelial cells, and hard-to-culture adherent lines.
Choose from trusted ECM protein and synthetic polymer coatings for endothelial, neural, stem cell, feeder-dependent, and general adherent cell culture workflows.
| Cat. No. | Product | Unit | Price |
|---|---|---|---|
| TM059 | Fibronectin Coating Solution (1 mg/mL) | 1.0 mg | $231.00 |
| TM060 | Vitronectin Coating Solution (0.5 mg/mL) | 0.2 mL | $628.00 |
| TM061 | Poly-L-Lysine Coating Solution (0.1%) | 25 mL | $75.00 |
| TM062 | Poly-L-Ornithine Coating Solution (0.1 mg/mL) | 50 mL | $269.00 |
| TM063 | Gelatin Coating Solution (0.1%) | 100 mL | $109.00 |
Use this guide as a starting point for selecting a coating based on your application, cell type, and culture format.
3DCelMatrix™ (TM076) is a basement membrane hydrogel for embedded or surface 3D culture.
Vitronectin (TM060) supports feeder-free hPSC culture; Applied Cell ECM (G422) supports multi-lineage differentiation.
Applied Cell ECM (G422) supports broad primary cell adhesion; Fibronectin (TM059) supports endothelial and mesenchymal cells.
Poly-L-Lysine (TM061) or Poly-L-Ornithine (TM062) may be used, optionally paired with laminin.
Fibronectin (TM059) or Gelatin (TM063) are common options for standard vascular endothelial culture.
Gelatin (TM063) is an economical choice for feeder-dependent and standard adherent cell lines.
Common questions about cell culture coatings, ECM-based matrices, iPSC support, coating application, and animal-component considerations.
Our technical team can help match your cell type, application, and culture format to the optimal coating solution.
