Cell Immortalization Reagents
Immortalized cells are highly preferred over primary cells due to their ability to provide unlimited, consistent access to the same cell line. This eliminates the issues of batch-to-batch variability and the high costs associated with primary cell use.
As a pioneer in cell immortalization technology, abm offers:
- A comprehensive library of immortalized cell lines for human, mouse, and other key research model organisms.
- Industry-leading immortalization reagents for researchers who wish to immortalize their own primary cells.
Our selection features the widest range of reagents and the highest quality standards—areas where competitors simply can't compare. Whether you're seeking ready-to-use cell lines or advanced tools to immortalize your own, abm has you covered.
Recombinant SV40T Virus
| Product Name | Cat. No. | Vector Map | Promoter | Marker | Price |
|---|---|---|---|---|---|
| Lentivirus | |||||
| Lenti-SV40T (Puro) Virus | LV613 | View | CMV | Puro | Inquire |
| Lenti-SV40T (Neo) Virus | LV660 | View | CMV | Neo | Inquire |
| Lenti-SV40T Virus | LV665 | View | CMV | Inquire | |
| Lenti-SV40Tt Virus | LV614 | View | CMV | Puro | Inquire |
| Lenti-SV40 Virus | LV612 | View | CMV | Inquire | |
| Lenti-SV40T (tsA58 temp sensitive) (Puro) Virus | LV630 | View | CMV | Puro | Inquire |
| Lenti-SV40T (tsA58 temp sensitive) Virus | LV680 | View |
CMV | Inquire | |
| Adenovirus | |||||
| Adeno-SV40T Virus | G210 | View | CMV | Puro | Inquire |
| Retrovirus | |||||
| Retro-SV40 Virus | G212 | View | 5'LTR | Neo | Inquire |
| Retro-SV40LT Virus | RVP010 | View | CMV | Puro | Inquire |
Recombinant hTERT Virus
| Product Name | Cat. No. | Vector Map | Promoter | Marker | Price |
|---|---|---|---|---|---|
| Lentivirus | |||||
| Lenti-hTERT-Puro Virus | LV615 | View | CMV | Puro | Inquire |
| Lenti-hTERT-Neo Virus | LV622 | View | CMV | Neo | Inquire |
| Lenti-hTERT Virus | LV674 | View | CMV | Inquire | |
| Lenti-hTERT-2A-CDK4 Virus | LV677 | View | CMV | Puro | Inquire |
| Lenti-EF1a-hTERT Virus | LV616 | View | EF1a | Puro | Inquire |
| Lenti-EF1a-hTERT-Hygro Virus | LV632 | View | EF1a | Hygro | Inquire |
| Adenovirus | |||||
| Adeno-hTERT Virus | G205 | View | CMV | Inquire | |
| Adeno-hTERT Antisense Virus | G208 | View | CMV | Inquire | |
Additional Immortalization Viruses
| Product Name | Cat. No. | Vector Map | Application | Price |
|---|---|---|---|---|
| HPV E6/E7 | ||||
| Lenti-HPV E6/E7 (Puro) Virus | LV617 | View | Immortalize keratinocytes | Inquire |
| Lenti-HPV E6/E7 Virus | LV667 | View | Inquire | |
| EBV genes (Epstein-Barr Virus) | ||||
| EBV Virus (Wild-Type) | G229 | N/A | Immortalize B lymphocytes, and sometimes T lymphocytes | Inquire |
| Adenoviral E1A-E1B | ||||
| E1A-E1B Lentivirus | LV652 | View | Immortalize a wide range of primary rodent cells, including amniotic fluid cells, epithelial cells, fibroblasts, and kidney cells | Inquire |
| siRNA | ||||
| Lenti-Rb siRNA Virus | LV621 | View | Co-express with hTERT for better immortalization of epithelial cells | Inquire |
| Lenti-p53 siRNA Virus | LV619 | View | Inquire | |
| Bmi1 | ||||
| Lenti-Bmi1 Virus | LV608 | View | Immortalize epithelial cells | Inquire |
| CDK4 | ||||
| Lenti-hTERT-2A-CDK4 Virus | LV677 | View | Co-express with hTERT for a more authentic cell model | Inquire |
| Lenti-CDK4 Virus | LV609 | View | Inquire | |
| Myc T58A (c-Myc), Ras V12 (H-Ras) | ||||
| Lenti-Myc T58A Virus | LV618 | View | Immortalizes a wide variety of cells, including neural stem cells, primary kidney cells, erythroblasts, and a variety of epithelial cells | Inquire |
| Lenti-Ras V12 Virus | LV620 | View | Inquire | |
| HOXB8, HOXA9, HOXA10 | ||||
| Lenti-HOXB8-RFP Virus | LV638 | View | Immortalize hematopoietic cells, including macrophages, hematopoetic progenitor cells, and myeloid progenitor cells | Inquire |
| Lenti-HOXA9-RFP Virus | LV644 | View | Inquire | |
| Lenti-HOXA10-RFP Virus | LV650 | View | Inquire | |
| Other Related Reagents | ||||
| ViralEntry™ Transduction Enhancer (100X) | G515 | Boosts lentiviral transduction | Inquire | |
Additional Information
-
Cell Immortalization Handbook
This Handbook provides an overview of methods, protocols, and reagents. -
Cell Immortalization Workflow
For more information, visit our Cell Immortalization Learning Resource. -
Custom Cell Immortalization Service
Our scientists can immortalize your cell line of choice.
Top Publications
Establishment and characterization of imortalized sweat gland myoepithelial cells.
Hayakawa T. et al.
Scientific Reports (2022)
doi: 10.1038/s41598-021-03991-5
Integrative analyses of human reprogramming reveal dynamic nature of induced pluripotency.
Cacchiarelli D. et al.
Cell (2015)
doi: 10.1016/j.cell.2015.06.016
Tumor-penetrating therapy for β5 integrin-rich pancreas cancer.
Hurtado T. et al.
Nature Communications (2021)
doi: 10.1038/s41467-021-21858-1