CRISPR sgRNA Library
abm's CRISPR Gene Knockout sgRNA vectors and viruses are highly effective at achieving knockout of your target gene. Cas9 functions to create a double-stranded break within an early exon triggering repair via Non-Homologous End-Joining (NHEJ) mechanism resulting in deleterious frameshift mutations. We offer a comprehensive collection of All-in-One (spCas9 and sgRNA expressing) and sgRNA only expressing constructs targeting any human, mouse, or rat gene. Can't find the construct you're looking for? Contact our team for a Custom sgRNA vector or virus.
Search CRISPR Knockout sgRNA Library
Search our collection of CRISPR knockout sgRNA products using gene name or accession number:
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Additional Information
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Performance/Data
Click to see our CRISPR Knockout Case Study, including experimental design and supporting data. -
Workflow
How to use abm's sgRNA lentivectors and lentiviruses in your CRISPR knockout experiment. -
Need Help Getting Started?
This handbook outlines guidelines for CRISPR sgRNA design and the experimental procedures needed to achieve a specific gene knockout.
Documents
Top Publications
Inferring and perturbing cell fate regulomes in human brain organoids.
Fleck JS. et al.
Nature (2022)
doi: 10.1038/s41586-022-05279-8
Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus.
Das A. et al.
Nature Microbiology (2020)
doi: 10.1038/s41564-020-0727-8
Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses.
Yamane D. et al.
Nature Microbiology (2019)
doi: 10.1038/s41564-019-0425-6