Cas Proteins & CRISPR Screening
- spCas9 Nuclease
- spCas9 Nickase
- spCas9 Null Mutant
- saCas9 Nuclease
- saCas9 Null Mutant
- Cas12a (Cpf1)
- CRISPR Kits
CRISPR is the most versatile technology for genome editing and abm offers the largest selection of Cas9 proteins for CRISPR experiments. Cas9 Ribonucleoproteins (RNPs) are Cas9 proteins in complex with in vitro transcribed sgRNA. These RNPs can be used for in vitro pre-screening sgRNA candidates and can be directly transfected or electroporated into cells to achieve gene editing.
Advantages of Cas9 RNP Delivery Method:
- No transcription or translation required, thus editing is rapid and transient
- No plasmid or virus is used, therefore no risk of genome integration of Cas9/sgRNA machinery
- Proteins are compatible with a wide range of organisms, no need to consider promoters & codon optimization
abm is continually developing a range of CRISPR-Cas proteins, including popular variants like Cas12a, Cas12b, Cas13a, and Cas13b, while also advancing high-fidelity options for precise genetic editing.
We also offer CRISPR screening kits that efficiently verify gene editing, saving valuable time, along with an sgRNA synthesis kit that includes all the necessary reagents for high-yield RNA transcription, ensuring seamless preparation for downstream CRISPR experiments.
Visit our knowledge base for more information about CRISPR-related technology.
| Product Name | Cat. No. | Quantity | Price |
|---|---|---|---|
| spCas9 Nuclease | |||
| Cas9 Nuclease Protein | K108 | 40 µg (250pmol/ 25 µL) | $80.00 |
| Cas9 Nuclease NLS Protein | K030 | 8.0 µg (50pmol/ 50 µL) | $40.00 |
| Cas9 Nuclease NLS Protein (High Concentration) | K130 | 40 µg (250pmol/ 25 µL) | $80.00 |
| Cas9 Nuclease NLS Protein (Lyophilized) | K151 | 200 µg (1.25 nmol) | $295.00 |
| Cas9 Nuclease GFP NLS Protein | K048 | 9.5 µg (50pmol/ 50 µL) | $55.00 |
| Cas9 Nuclease GFP NLS Protein (High Concentration) | K148 | 47 µg (250pmol/ 25 µL) | $155.00 |
| spCas9 Nickase | |||
| Cas9 Nickase D10A Protein | K132 | 40 µg (250pmol/ 25 µL) | $135.00 |
| Cas9 Nickase D10A NLS Protein | K134 | 40 µg (250pmol/ 25 µL) | $135.00 |
| Cas9 Nickase D10A GFP NLS Protein | K149 | 47 µg (250pmol/ 25 µL) | $155.00 |
| Cas9 Nickase H840A Protein | K136 | 40 µg (250pmol/ 25 µL) | $135.00 |
| Cas9 Nickase H840A NLS Protein | K138 | 40 µg (250pmol/ 25 µL) | $135.00 |
| spCas9 Null Mutant | |||
| Cas9 Null Mutant Protein | K140 | 40 µg (250pmol/ 25 µL) | $135.00 |
| Cas9 Null Mutant NLS Protein | K142 | 40 µg (250pmol/ 25 µL) | $135.00 |
| Cas9 Null Mutant GFP NLS Protein | K086 | 9.5 µg (50pmol/ 50 µL) | $55.00 |
| Cas9 Null Mutant GFP NLS Protein (High Concentration) | K186 | 47 µg (250pmol/ 25 µL) | $155.00 |
| saCas9 Nuclease | |||
| saCas9 Nuclease Protein | K044 | 6.5 µg (50pmol/ 50 µL) | $55.00 |
| saCas9 Nuclease Protein (High Concentration) | K144 | 32.5 µg (250pmol/ 25 µL) | $155.00 |
| saCas9 Nuclease NLS Protein | K189 | 32.5 µg (250pmol/ 50 µL) | $155.00 |
| saCas9 Nuclease NLS Protein (Lyophilized) | K152 | 32.5 µg (250pmol) | $185.00 |
| saCas9 Null Mutant | |||
| saCas9 Null Mutant Protein | K146 | 32.5 µg (250pmol/ 25 µL) | $155.00 |
| saCas9 Null Mutant NLS Protein | K147 | 32.5 µg (250pmol/ 25 µL) | $155.00 |
| Cas12a (Cpf1) | |||
| Cas12a (asCpf1) Nuclease NLS Protein | K188 | 380 µg (2.5 nmol/ 250 µL) | $365.00 |
| Cas12a (fnCpf1) Nuclease NLS Protein | K187 | 380 µg (2.5 nmol/ 250 µL) | $365.00 |
| CRISPR Kits | |||
| Screen It™ CRISPR Cas9 Cleavage Detection Kit | G990 | 100 Reactions | $705.00 |
| CRISPR Genomic Cleavage Detection Kit | G932 | 100 Reactions | $170.00 |
| sgRNA Synthesis Kit, spCas9 | G520 | 10 Reactions | $99.00 |
Resources
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