siRNA Technology 

siRNAs are powerful tools for gene silencing and can be delivered to the target cell or host via a variety of methods including ready-to-use recombinant lentivirus and AAV or direct transfection of DNA plasmids or double stranded RNA (dsRNA). Our unique convergent dual promoter system avoids the need to design hair-pin loop shRNA structures, streamlining cloning and knockdown of the target gene.

We offer a comprehensive collection of human, mouse, and rat siRNAs pre-designed for knockdown of your gene of interest. Can't find what you're looking for? We offer Custom siRNA vectors and viruses tailored to your experiment.

Search our collection of siRNA Technology products using Gene symbol or Accession number:

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Additional Products

Resources

  • Viral Expression Systems Brochure
    Viral Expression Systems Brochure
    Introductory Guide

  • piLenti-siRNA-GFP vector map
    Vector Map
  • Lenti-siRNA Expression Systems
    Lenti-siRNA Expression Systems Manual
    Click to Download

Top Publications

01 Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform.

Da Li et al.
Nature Communications (2020)


doi: 10.1038/s41467-019-14185-z
02 FSH blockade improves cognition in mice with Alzheimer's disease.

Xiong J. et al.
Nature (2022)


doi: 10.1038/s41586-0225-04463-0
03

Sphingosine-1-phosphate receptor 3 in the medial prefrontal cortex promotes stress resilience by reducing inflammatory processes.

Corbett BF. et al.
Nature Communications (2019)

doi: 10.1038/s41467-019-10904-8