Trypsin Neutralizing Solution
Cat. No.
|
TM069
Print
|
Name
|
Trypsin Neutralizing Solution
|
Description
|
Trypsin Neutralizing Solution is a high-quality, ready-to-use reagent designed to effectively neutralize the activity of trypsin following cell dissociation. Ideal for use in cell culture applications, this solution provides a gentle and efficient means of halting enzymatic activity after trypsinization, preserving cell viability and function. The formula is optimized for the rapid inactivation of trypsin, ensuring minimal impact on cell health and morphology. Perfect for use in various cell culture protocols, this product is an essential tool for maintaining the integrity of cells post-trypsinization.
Key Features:
-
Rapidly neutralizes trypsin activity
-
Preserves cell viability and morphology
-
Suitable for a variety of cell types
-
Convenient, ready-to-use solution
-
Ideal for routine cell passaging and subculturing
|
Unit
|
100 ml
|
Sterility
|
Pass
|
Appearance
|
Liquid
|
Application
|
For Research Use Only.
|
Shipping Conditions
|
Ship with Dry Ice.
|
QC
|
Each lot has been fully tested and optimized for its ability to support in vitro cell culture. The testing parameters include: adherence rate (where applicable), typical morphology, and metabolism of the tested cells. Additionally, the media has been tested for sterility, pH, osmolality and endotoxin levels.
|
Storage Condition
|
Store at or below -20°C. Do not thaw and refreeze.
|
Caution
|
For research use only and is not intended for therapeutic or diagnostic applications. abm products are intended for laboratory research purposes only, unless noted otherwise. They are not intended for use in humans. abm makes no warranties or representations as to the accuracy of the information on this site. Citations from literature are provided for informational purposes only. abm does not warrant that such information has been shown to be accurate.
|
Disclaimer
|
1. Sale of this item is subjected to the completion of a Material Transfer Agreement (MTA) by the purchasing individual/institution for each cell line. If you have any questions regarding this, please contact us at licensing@abmgood.com.
2. All test parameters provided in the CoA are conducted using abm's standardized culture system and The stated values may vary under the end-user's culture conditions. Please verify that the product is suitable for your studies by referencing published papers or ordering RNA (0.5 μg, Cat.# C207, $450.00) or cell lysate (100 μg, Cat.# C206, $600.00) to perform preliminary experiments, or alternatively use our Gene Expression Assay Service (Cat# C138). All sales are final.
3. We recommend live cell shipments for ease of cell transfer and this option can be requested at the time of order placement. Please note that the end-user will need to evaluate the feasibility of live cell shipment by taking into account the final destination's temperature variation and its geographical location.
4. All of abm's cell biology products are for research use ONLY and NOT for therapeutic/diagnostic applications. abm is not liable for any repercussions arising from the use of its cell biology product(s) in therapeutic/diagnostic or any other non-RUO application(s).
5. abm makes no warranties or representations as to the accuracy of the information on this site. Citations from literature are provided for informational purposes only. abm does not warrant that such information has been shown to be accurate.
6. abm warrants that cell lines shall be viable upon initiation of culture for a period of thirty (30) days after shipment and that they shall meet the specifications on the applicable abm Material Product Information sheet, certificate of analysis, and/or catalog description. Such thirty (30) day period is referred to herein as the "Warranty Period".
|
Material Citation
|
If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. TM069
|
There are no Documents for this product yet!
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:
UNIT
25/Bag, 40 Bags/Case
UNIT
10 Dishes/Pack, 12 Packs/Case
{"id":51454,"cat_no":"TM069","retired_cat_no":"","old_cat_no":"TM069","name":"Trypsin Neutralizing Solution","price":"170.0000","price_before_discount":"0.0000","academic_price":"0.00","commercial_price":"0.00","distributor_price_note":"","unit_quantity":"100 ml","category_id":229,"category_name":"Trypsin","frontend_category_id":36,"frontend_category_ids":"20,33,36","gene_id":0,"ncbi_id":0,"gene_name":"","gene_full_name":"","alias":"","accession_number":"","species_id":0,"species":"","real_species_id":0,"cell_type_id":0,"cell_type":"","product_type":"","tissue_id":0,"tissue":"","tissue_system":"","source":null,"keywords":"","invisible_search_keywords":"","filter_group_id":13,"filter_group_name":"Cell Lines","filter_name":"Media \u0026 Supplements","search_filter_ids":"41,42","search_filter_keys":"41-42","temp_field":null,"filter_id":20,"customization":0,"filter_table_id":18125830,"filter_table_name":"","related_group_id":0,"operator":"","status":1,"is_ko":0,"need_remove":0,"units":null,"document_sort":"","price_old":"0.0000","price2024":"0.0000","created_at":"2022-12-07 03:05:48","updated_at":"2025-04-02 17:32:05","points_rule":1,"Confirmed":"Need Confirm","application_no_use":null,"application_id_no_use":null,"raised_in":null,"raised_in_id":null,"geo_price_before_discount":"0.00","geo_titer7_price_before_discount":"149.00","cate_url":"Trypsin.html","frontendBreadcrumbs":[{"id":20,"pid":86,"name":"Cellular Materials","page_id":18,"page_type":"App\\Models\\Category","href":"","sort":20,"show_in_nav":1,"show_in_homepage":1,"has_children":1,"status":1,"related_table":null,"created_at":null,"updated_at":null,"url_key":"cellular-materials.html","url":"cellular-materials.html"},{"id":33,"pid":20,"name":"Media \u0026 Supplements","page_id":26,"page_type":"App\\Models\\Category","href":null,"sort":33,"show_in_nav":1,"show_in_homepage":1,"has_children":1,"status":1,"related_table":null,"created_at":null,"updated_at":"2025-03-03 23:30:07","url_key":"Media-and-Supplements.html","url":"Media-and-Supplements.html"},{"id":36,"pid":33,"name":"Trypsin","page_id":229,"page_type":"App\\Models\\Category","href":null,"sort":5,"show_in_nav":1,"show_in_homepage":1,"has_children":0,"status":1,"related_table":null,"created_at":null,"updated_at":"2025-02-25 18:08:33","url_key":"Trypsin.html","url":"Trypsin.html"}],"price_flag":0,"builderURL":"","builderViewerURL":"","mapURL":"","viewerURL":"","builderType":"","productType":"App\\Models\\CatalogBaseCells","info_family":"","geo_price":"170.00","geo_price_symbol":"$170.00","category":{"id":229,"categories":"Trypsin","pid":18,"url_key":"Trypsin.html","css":null,"wid":0,"breadcrumbs":null,"breadcrumbsIdJson":"","breadcrumbsHtml":"","description":"\u003Ch2 class=\u0022abm-categories-title-h2\u0022\u003ETrypsin\u003C\/h2\u003E\n\u003Cdiv class=\u0022\u0022\u003E\n\u003Cdiv id=\u0022ProductList\u0022\u003E\n\u003Cdiv class=\u0022tr-white abm-custom-page-tr\u0022 id=\u0022MycoDetection\u0022\u003E\n\u003Cdiv class=\u0022\u0022\u003E\n\u003Cdiv class=\u0022abm-custom-page-block-div\u0022\u003E\n\u003Cdiv class=\u0022col-sm-12 col-md-12 abm-custom-page-padding-left-zero\u0022\u003E\n\u003Cdiv class=\u0022abm-custom-page-align-left\u0022\u003E\n\u003Cdiv class=\u0022row\u0022\u003E\n\u003Cdiv class=\u0022col-xs-12 col-sm-12 col-md-12 col-lg-12\u0022\u003E\n\u003Cdiv class=\u0022abm-custom-page-align-left abm-custom-p\u0022\u003E\n\u003Cp class=\u0022abm-custom-page-p\u0022\u003ETrypsin, a proteolytic enzyme, is the standard way to detach adherent cell cultures and monolayers. This globular, pancreatic protease cleaves at the C-terminal side of lysine and arginine, breaking down vessel-adhering proteins and allowing easy resuspension during cell harvesting.\u003C\/p\u003E\n\u003Cp class=\u0022abm-custom-page-p\u0022\u003E\u003Cstrong\u003Eabm\u003C\/strong\u003E offers porcine-derived trypsin, EDTA-enhanced trypsin, as well as formulations of a gentle, trypsin-like enzyme. To avoid unplanned protein degradation, organic trypsin must be inactivated with trypsin inhibitors. In contrast, synthetic trypsin is deactivated via dilution, eliminating the need for additional solutions.\u003C\/p\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003Cdiv class=\u0022abm-container-fluid\u0022\u003E\n\u003Ch3 class=\u0022abm-custom-page-h1 abm-custom-page-align-left abm-custom-page-product-name\u0022\u003E\u003Cstrong\u003EProduct List\u003C\/strong\u003E\u003C\/h3\u003E\n\u003Cdiv class=\u0022table-responsive\u0022\u003E\n\u003Ctable class=\u0022abm-perfect-table1 bootstrap-table bootstrap-table-hover abm-service-table\u0022\u003E\n\u003Cthead\u003E\n\u003Ctr\u003E\n\u003Cth style=\u0022width: 55%;\u0022\u003EProduct Name\u003C\/th\u003E\n\u003Cth style=\u0022width: 15%;\u0022\u003ECat. No.\u003C\/th\u003E\n\u003Cth style=\u0022width: 15%;\u0022\u003EQuantity\u003C\/th\u003E\n\u003Cth style=\u0022width: 15%;\u0022\u003EPrice\u003C\/th\u003E\n\u003C\/tr\u003E\n\u003C\/thead\u003E\n\u003Ctbody\u003E\n\u003Ctr\u003E\n\u003Ctd\u003E\u003Ca class=\u0022orange-link\u0022 href=\u0022\/prigrow-xiii-medium-5.html\u0022\u003ETrypsin Neutralizing Solution\u003C\/a\u003E\u003C\/td\u003E\n\u003Ctd\u003E\u003Ca class=\u0022orange-link\u0022 href=\u0022\/prigrow-xiii-medium-5.html\u0022\u003ETM069\u003C\/a\u003E\u003C\/td\u003E\n\u003Ctd\u003E100 ml\u003C\/td\u003E\n\u003Ctd class=\u0022product-price\u0022 data-product=\u0022TM069\u0022\u003E\u003C\/td\u003E\n\u003C\/tr\u003E\n\u003Ctr\u003E\n\u003Ctd\u003E\u003Ca class=\u0022orange-link\u0022 href=\u0022\/trypsin-edta-tm050.html\u0022\u003ETrypsin-EDTA (0.25%)\u003C\/a\u003E\u003C\/td\u003E\n\u003Ctd\u003E\u003Ca class=\u0022orange-link\u0022 href=\u0022\/trypsin-edta-tm050.html\u0022\u003ETM050\u003C\/a\u003E\u003C\/td\u003E\n\u003Ctd\u003E500 ml\u003C\/td\u003E\n\u003Ctd class=\u0022product-price\u0022 data-product=\u0022TM050\u0022\u003E\u003C\/td\u003E\n\u003C\/tr\u003E\n\u003Ctr\u003E\n\u003Ctd\u003E\u003Ca class=\u0022orange-link\u0022 href=\u0022\/prigrow-xiii-medium-1.html\u0022\u003EGentle Dissociation Solution\u003C\/a\u003E\u003C\/td\u003E\n\u003Ctd\u003E\u003Ca class=\u0022orange-link\u0022 href=\u0022\/prigrow-xiii-medium-1.html\u0022\u003ETM080\u003C\/a\u003E\u003C\/td\u003E\n\u003Ctd\u003E100 ml\u003C\/td\u003E\n\u003Ctd class=\u0022product-price\u0022 data-product=\u0022TM080\u0022\u003E\u003C\/td\u003E\n\u003C\/tr\u003E\n\u003C\/tbody\u003E\n\u003C\/table\u003E\n\u003Ch3 class=\u0022abm-custom-page-h1 abm-custom-page-align-left abm-custom-page-product-name\u0022 style=\u0022margin-bottom: 20px;\u0022\u003E\u003Cstrong\u003ETrypsin inhibitors\u003C\/strong\u003E\u003C\/h3\u003E\n\u003Cp class=\u0022abm-mt-5\u0022\u003ETrypsin inhibitors destructively alter trypsin, nullifying the proteolytic enzyme\u0026rsquo;s ability to bind with, and so digest, proteins. Used post dissociation, trypsin inhibitors protect your cells against further protein degradation by trypsin.\u003C\/p\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003Cp\u003E\n\u003Cscript\u003E\n const catNoList = [];\n document.querySelectorAll(\u0027.product-price\u0027).forEach(el =\u003E {\n if (el.dataset.product) {\n el.innerHTML = \u0027Inquiry\u0027;\n if (el.dataset.type) {\n catNoList.push({\n type: el.dataset.type,\n value: el.dataset.product,\n });\n } else {\n catNoList.push(el.dataset.product);\n }\n }\n });\n fetch(\u0027\/product\/geoPrice\u0027, {\n method: \u0027post\u0027,\n body: JSON.stringify({ cat_no: catNoList, _token: document.querySelector(\u0027meta[name=\u0022X-CSRF-TOKEN\u0022]\u0027).content, type: \u0027cells\u0027 }),\n headers: {\n \u0027Content-Type\u0027: \u0027application\/json\u0027,\n }\n }).then(res =\u003E {\n const json = res.json();\n json.then(response =\u003E {\n if (response.code === 0) {\n const result = response.result;\n for (const key in result) {\n document.querySelectorAll(\u0027.product-price[data-product=\u0022\u0027 + key + \u0027\u0022]\u0027).forEach(el =\u003E {\n el.innerHTML = \u0027$\u0027 + result[key];\n });\n }\n }\n });\n });\n \u003C\/script\u003E\n\u003C\/p\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E","meta_title":"Trypsin","meta_keywords":"Trypsin","meta_description":"Trypsin","deleted_at":null,"enable":"Y","parent_list":"18","table_name":null,"image":null,"independentPage":0,"top_type":0,"sort_order":null,"in_footer":0,"fid":null,"created_at":"2024-12-13 08:38:34","updated_at":"2025-04-02 01:04:45"},"info":{"id":5402,"cat_no_base":"TM069","parent_id":51454,"image":null,"price-original":null,"description":"\u003Cp class=\u0022\u0022 data-start=\u002235\u0022 data-end=\u0022649\u0022\u003ETrypsin Neutralizing Solution is a high-quality, ready-to-use reagent designed to effectively neutralize the activity of trypsin following cell dissociation. Ideal for use in cell culture applications, this solution provides a gentle and efficient means of halting enzymatic activity after trypsinization, preserving cell viability and function. The formula is optimized for the rapid inactivation of trypsin, ensuring minimal impact on cell health and morphology. Perfect for use in various cell culture protocols, this product is an essential tool for maintaining the integrity of cells post-trypsinization.\u003C\/p\u003E\n\u003Cp class=\u0022\u0022 data-start=\u0022651\u0022 data-end=\u0022668\u0022\u003E\u003Cstrong data-start=\u0022651\u0022 data-end=\u0022668\u0022\u003EKey Features:\u003C\/strong\u003E\u003C\/p\u003E\n\u003Cul data-start=\u0022669\u0022 data-end=\u0022876\u0022\u003E\n\u003Cli class=\u0022\u0022 data-start=\u0022669\u0022 data-end=\u0022707\u0022\u003E\n\u003Cp class=\u0022\u0022 data-start=\u0022671\u0022 data-end=\u0022707\u0022\u003ERapidly neutralizes trypsin activity\u003C\/p\u003E\n\u003C\/li\u003E\n\u003Cli class=\u0022\u0022 data-start=\u0022708\u0022 data-end=\u0022749\u0022\u003E\n\u003Cp class=\u0022\u0022 data-start=\u0022710\u0022 data-end=\u0022749\u0022\u003EPreserves cell viability and morphology\u003C\/p\u003E\n\u003C\/li\u003E\n\u003Cli class=\u0022\u0022 data-start=\u0022750\u0022 data-end=\u0022788\u0022\u003E\n\u003Cp class=\u0022\u0022 data-start=\u0022752\u0022 data-end=\u0022788\u0022\u003ESuitable for a variety of cell types\u003C\/p\u003E\n\u003C\/li\u003E\n\u003Cli class=\u0022\u0022 data-start=\u0022789\u0022 data-end=\u0022824\u0022\u003E\n\u003Cp class=\u0022\u0022 data-start=\u0022791\u0022 data-end=\u0022824\u0022\u003EConvenient, ready-to-use solution\u003C\/p\u003E\n\u003C\/li\u003E\n\u003Cli class=\u0022\u0022 data-start=\u0022825\u0022 data-end=\u0022876\u0022\u003E\n\u003Cp class=\u0022\u0022 data-start=\u0022827\u0022 data-end=\u0022876\u0022\u003EIdeal for routine cell passaging and subculturing\u003C\/p\u003E\n\u003C\/li\u003E\n\u003C\/ul\u003E","shipment_type":null,"internal_leadtime":"0","lysate_type":null,"small_image":null,"growth_factor_size":null,"gene_name_no_use":null,"mammalian_selection_marker":null,"mammalian_selection_text":null,"storage_condition":"Store at or below -20\u00b0C.\u00a0Do not thaw and refreeze.","str_profiles":null,"species_description":null,"cost":null,"note":null,"family":null,"overexpressed_gene":null,"diameter":null,"appearance":"Liquid","pluripotency":null,"recommended_medium_volume":null,"medium":null,"alias":null,"tier_price":null,"operator_no_use":null,"addtime":null,"cell_line":null,"price_type":null,"gallery":null,"cell_growth_area":null,"cell_morphology":null,"expression_system_type":null,"gene_symbol":null,"insert_size":null,"msrp":null,"msrp_display_actual_price_type":null,"cell_morphology_specification":null,"tax_class_id":null,"inventory_location":null,"vector":null,"internal_note":null,"component":null,"quantity_and_stock_status":null,"vector_url":null,"application":"\u003Cp\u003EFor Research Use Only.\u003C\/p\u003E","minimal_price":null,"seeding_density":null,"seeding_density_cm":null,"seeding_density_ml":null,"source":null,"source_catno":"Cell Applications 080-100","osmolarity":null,"weight":null,"royalty_rates":null,"population_doubling_time":null,"source_price":null,"weight_type":null,"ph":null,"licensor_commission_rate":null,"supplier":null,"donor_gender":null,"appearance_general":"Clear","sterility":"Pass","molecular_weight":null,"endotoxin_level":null,"donor_age":null,"news_from_date":null,"news_to_date":null,"expression_system_general":null,"donor_disease":null,"purity":null,"country_of_manufacture":null,"donor_ethnicity":null,"image_label":null,"biological_activity_text":null,"cart2quote_quotable":"2","biosafety":null,"product_quote":0,"small_image_label":null,"immortalization_method":null,"bioactivity_data":null,"formulation":null,"thumbnail_label":null,"mammalian_selection":null,"isolation_method":null,"function":null,"reconstitution":null,"growth_properties":null,"expression_profile":null,"storage":null,"propagation_method":null,"usage":null,"freeze_thaw_recovery":null,"str_profile":null,"str_markers":"","subculture_protocol":null,"preservation_protocol":null,"passage_number":null,"qc":"\u003Cp\u003EEach lot has been fully tested and optimized for its ability to support in vitro cell culture. The testing parameters include: adherence rate (where applicable), typical morphology, and metabolism of the tested cells. Additionally, the media has been tested for sterility, pH, osmolality and endotoxin levels.\u003C\/p\u003E","shipping_conditions":"\u003Cp\u003EShip with Dry Ice.\u003C\/p\u003E","disclaimer_general":"\u003Cp\u003E1. Sale of this item is subjected to the completion of a Material Transfer Agreement (MTA) by the purchasing individual\/institution for each cell line. If you have any questions regarding this, please contact us at \u003Ca href=\u0022mailto:licensing@abmgood.com\u0022\u003Elicensing@abmgood.com\u003C\/a\u003E.\u003C\/p\u003E\n\u003Cp\u003E2. All test parameters provided in the CoA are conducted using \u003Cstrong\u003Eabm\u003C\/strong\u003E\u0027s standardized culture system and The stated values may vary under the end-user\u0027s culture conditions. Please verify that the product is suitable for your studies by referencing published papers or ordering RNA (0.5 \u0026mu;g, Cat.# C207, $450.00) or cell lysate (100 \u0026mu;g, Cat.# C206, $600.00) to perform preliminary experiments, or alternatively use our Gene Expression Assay Service (Cat# C138). All sales are final.\u003C\/p\u003E\n\u003Cp\u003E3. We recommend live cell shipments for ease of cell transfer and this option can be requested at the time of order placement. Please note that the end-user will need to evaluate the feasibility of live cell shipment by taking into account the final destination\u0027s temperature variation and its geographical location.\u003C\/p\u003E\n\u003Cp\u003E4. All of \u003Cstrong\u003Eabm\u003C\/strong\u003E\u0027s cell biology products are for research use ONLY and NOT for therapeutic\/diagnostic applications. \u003Cstrong\u003Eabm\u003C\/strong\u003E is not liable for any repercussions arising from the use of its cell biology product(s) in therapeutic\/diagnostic or any other non-RUO application(s).\u003C\/p\u003E\n\u003Cp\u003E5. \u003Cstrong\u003Eabm\u003C\/strong\u003E makes no warranties or representations as to the accuracy of the information on this site. Citations from literature are provided for informational purposes only. \u003Cstrong\u003Eabm\u003C\/strong\u003E does not warrant that such information has been shown to be accurate.\u003C\/p\u003E\n\u003Cp\u003E6. \u003Cstrong\u003Eabm\u003C\/strong\u003E warrants that cell lines shall be viable upon initiation of culture for a period of thirty (30) days after shipment and that they shall meet the specifications on the applicable \u003Cstrong\u003Eabm\u003C\/strong\u003E Material Product Information sheet, certificate of analysis, and\/or catalog description. Such thirty (30) day period is referred to herein as the \u0022Warranty Period\u0022.\u003C\/p\u003E","caution":"\u003Cp\u003EFor research use only and is not intended for therapeutic or diagnostic applications. \u003Cbr \/\u003E\u003Cstrong\u003Eabm\u003C\/strong\u003E\u0026nbsp;products are intended for laboratory research purposes only, unless noted otherwise. They are not intended for use in humans.\u003Cbr \/\u003E\u003Cstrong\u003Eabm\u003C\/strong\u003E\u0026nbsp;makes no warranties or representations as to the accuracy of the information on this site. Citations from literature are provided for informational purposes only.\u0026nbsp;\u003Cstrong\u003Eabm\u003C\/strong\u003E\u0026nbsp;does not warrant that such information has been shown to be accurate.\u003C\/p\u003E","transfection_reagents_type":null,"licensed_by":null,"licensed_from":null,"licensing_institution":null,"guarantee":null,"depositor":null,"licensor_name":null,"licensor_contact_information":null,"contract_termination_date":null,"links_purchased_separately":null,"samples_title":null,"links_title":null,"links_exist":null,"internal_supplier":null,"internal_product_note":null,"donor_history":null,"split_ratio":null,"expression":null,"growth_conditions":null,"recommend":null,"references":null,"cryopreservation":null,"unpacking_storage_instructions":null,"promotions":null,"sync_images":null,"thawing_protocol":null,"type_online":null,"parental_cell_line":null,"mutation_and_validations":null,"knockout_method":null,"clone_no":null,"created_at":"2022-12-08 03:03:36","updated_at":"2025-04-02 17:32:05","concentration":null},"seo":{"id":73920,"catalog_id":51454,"catalog_type":"App\\Models\\CatalogBaseCells","url_key":"prigrow-xiii-medium-5.html","meta_title":"Trypsin Neutralizing Solution","meta_keywords":"Trypsin Neutralizing Solution","meta_description":"Trypsin Neutralizing Solution","created_at":"2023-01-05 05:38:34","updated_at":"2025-03-26 23:38:54"},"maps":[],"media":[{"id":386306,"parent_id":51454,"parent_type":"App\\Models\\CatalogBaseCells","file_path":"\/upload\/zMjn6ZHkr6PcX26BypBr3ZhNaIp5UkPAjaX3yw8L.png","title":null,"text":null,"file_type":"image","alt":null,"url":null,"position":null,"status":1,"entity_id_m2":null,"sku_in_m2":null,"value_id_m2":null,"attribute_id":0,"created_at":"2025-01-16 21:21:47","updated_at":"2025-01-16 21:21:47"}],"gene":null}