CRISPRa dCas9-VPR Lentivirus

{"id":3382,"cat_no":"K098","sku_in_m2":"","old_cat_no":"","name":"CRISPRa dCas9-VPR Lentivirus","category_id":239,"category_name":"Cas9 Vectors \u0026 Virus","frontend_category_id":70,"frontend_category_ids":"86,57,67,70","gene_id":0,"gene_name":"","gene_full_name":"","alias":"","unit_quantity":"4 x 500\u00b5l","accession_number":"","species_id":0,"species":"","raised_in_id":0,"raised_in":"","cell_type_id":0,"cell_type":"","tissue_id":0,"tissue":"","price":"643.0000","price_before_discount":"795.0000","keywords":"cas9 vectors and viruses","invisible_search_keywords":"K015, K016, dCas9-SAM, dCas9-VPR, dCas9-SAM lentivector, dCas9-SAM lentivirus, dCas9-VPR lentivector, dCas9-VPR lentivirus, SAM, VPR, CRISPRa, CRISPR activation, dCas9, dead cas9, double mutant cas9, cas9 null mutant, dcas9 lentivector, dcas9 lentivirus.","filter_group_id":34,"filter_group_name":"Molecular Biology","filter_id":67,"filter_name":"Expression Systems","search_filter_ids":"55,56","search_filter_keys":"55-56","temp_field":null,"customization":0,"filter_table_id":0,"filter_table_name":"","related_group_id":null,"url":"","operator":"","points_rule":5,"status":1,"need_remove":0,"document_sort":"","price_old":null,"price2024":null,"created_at":"2024-03-13 23:13:09","updated_at":"2025-01-06 08:34:41","Confirmed":"Need Confirm","geo_price_before_discount":"795.00","geo_titer7_price_before_discount":"944.00","cate_url":"cas9-expression-vectors-and-viruses.html","frontendBreadcrumbs":[{"id":57,"pid":86,"name":"Genetic Materials","page_id":8,"page_type":"App\\Models\\Category","href":null,"sort":57,"show_in_nav":1,"show_in_homepage":1,"has_children":1,"status":1,"related_table":null,"created_at":null,"updated_at":"2025-01-20 08:46:24","url_key":"genetic-materials.html","url":"genetic-materials.html"},{"id":67,"pid":57,"name":"CRISPR","page_id":15,"page_type":"App\\Models\\Category","href":null,"sort":67,"show_in_nav":1,"show_in_homepage":1,"has_children":1,"status":1,"related_table":null,"created_at":null,"updated_at":null,"url_key":"CRISPR-Cas9-sgRNA.html","url":"CRISPR-Cas9-sgRNA.html"},{"id":70,"pid":67,"name":"Cas9 Vectors \u0026 Virus","page_id":111,"page_type":"App\\Models\\Cms","href":null,"sort":70,"show_in_nav":1,"show_in_homepage":1,"has_children":0,"status":1,"related_table":null,"created_at":null,"updated_at":null,"url_key":"cas9-expression-vectors-and-viruses.html","url":"cas9-expression-vectors-and-viruses.html"}],"price_flag":0,"builderURL":"","builderViewerURL":"\/vds\/viewer\/cat\/261?embed=1","mapURL":"\/vds\/map\/cat\/261","viewerURL":"\/vds\/viewer\/cat\/261","builderType":"","productType":"App\\Models\\CatalogBaseMolecular","geo_price":"643.00","geo_price_symbol":"$643.00","category":{"id":239,"categories":"Cas9 Vectors \u0026 Virus","pid":15,"url_key":"cas9-expression-vectors-and-viruses.html","css":null,"wid":0,"breadcrumbs":null,"breadcrumbsIdJson":"","breadcrumbsHtml":"","description":null,"meta_title":"Cas9 Vectors \u0026 Virus","meta_keywords":"Cas9 Vectors \u0026 Virus","meta_description":"Cas9 Vectors \u0026 Virus","deleted_at":null,"enable":"N","parent_list":"8,15","table_name":null,"image":null,"independentPage":0,"top_type":0,"sort_order":null,"in_footer":0,"fid":null,"created_at":"2024-12-20 01:58:15","updated_at":"2024-12-20 02:01:54"},"info":{"id":18560,"cat_no_base":null,"parent_id":3382,"description":"\u003Cp\u003EThis Cas9 Double Mutant (dCas9) carries the mutations D10A and H840A which inactivates both nuclease and nickase activities. Using a target-specific guide RNA (sgRNA), it can bind to a specific genomic position without inducing DNA cleavage. In this construct, dCas9 is fused to the tripartite complex VPR (\u003Cspan style=\u0022text-decoration: underline;\u0022\u003EV\u003C\/span\u003EP64, \u003Cspan style=\u0022text-decoration: underline;\u0022\u003Ep\u003C\/span\u003E65 and \u003Cspan style=\u0022text-decoration: underline;\u0022\u003ER\u003C\/span\u003Eta). These transcriptional activators work in tandem to recruit transcription factors which in turn up-regulate expression of your gene of interest. In comparison to dCas9-SAM system, dCas9-VPR does not require specialized MS2 sgRNAs and it allows for streamlined transfection or infection as the vector encodes a single fusion protein.\u003C\/p\u003E","disclaimer":"\u003Ca href=\u0022\/terms#disclaimer-section\u0022\u003EClick for more info\u003C\/a\u003E","application":null,"components":null,"cas9_origin":null,"concentration":null,"enzymes_size":null,"genecraft_series":null,"guarantee":"","population":null,"qc":null,"format_general":null,"including_screening_kit":null,"expression_system_general":null,"purity":null,"image":null,"insert_size":null,"shipping_conditions":null,"source_catalog_number":null,"inactivation_protocol":null,"led_viewer_compatibility":null,"unit_definition":null,"vector":"pLenti-SFFV-dCas9-VPR","reaction_buffer":null,"storage_buffer":null,"caution":"This product is for research use only and is not intended for therapeutic or diagnostic applications. 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