dCas9-KRAB Lentiviral Vector

{"id":2723,"cat_no":"K203","sku_in_m2":"","old_cat_no":"K203","name":"dCas9-KRAB Lentiviral Vector","category_id":239,"category_name":"Cas9 Vectors \u0026 Virus","frontend_category_id":70,"frontend_category_ids":"57,67,70","gene_id":0,"gene_name":"","gene_full_name":"","alias":"","unit_quantity":"10 \u00b5g","accession_number":"","species_id":0,"species":"","raised_in_id":0,"raised_in":"","cell_type_id":0,"cell_type":"","tissue_id":0,"tissue":"","price":"212.0000","price_before_discount":"0.0000","keywords":"cas9 vectors and viruses","invisible_search_keywords":"dcas9-krab, dcas9 krab","filter_group_id":34,"filter_group_name":"Molecular Biology","filter_id":67,"filter_name":"Expression Systems","search_filter_ids":"55,56","search_filter_keys":"55-56","temp_field":null,"customization":0,"filter_table_id":18080827,"filter_table_name":"","related_group_id":15,"url":"","operator":"","points_rule":6,"status":1,"need_remove":0,"document_sort":"","price_old":"195.0000","price2024":"205.0000","created_at":null,"updated_at":"2025-04-03 20:30:27","Confirmed":"Need Confirm","geo_price_before_discount":"0.00","geo_titer7_price_before_discount":"149.00","cate_url":"cas9-expression-vectors-and-viruses.html","frontendBreadcrumbs":[{"id":57,"pid":86,"name":"Genetic Materials","page_id":8,"page_type":"App\\Models\\Category","href":null,"sort":57,"show_in_nav":1,"show_in_homepage":1,"has_children":1,"status":1,"related_table":null,"created_at":null,"updated_at":"2025-01-20 08:46:24","url_key":"genetic-materials.html","url":"genetic-materials.html"},{"id":67,"pid":57,"name":"CRISPR","page_id":15,"page_type":"App\\Models\\Category","href":null,"sort":67,"show_in_nav":1,"show_in_homepage":1,"has_children":1,"status":1,"related_table":null,"created_at":null,"updated_at":null,"url_key":"CRISPR-Cas9-sgRNA.html","url":"CRISPR-Cas9-sgRNA.html"},{"id":70,"pid":67,"name":"Cas9 Vectors \u0026 Virus","page_id":111,"page_type":"App\\Models\\Cms","href":null,"sort":70,"show_in_nav":1,"show_in_homepage":1,"has_children":0,"status":1,"related_table":null,"created_at":null,"updated_at":null,"url_key":"cas9-expression-vectors-and-viruses.html","url":"cas9-expression-vectors-and-viruses.html"}],"price_flag":0,"builderURL":"","builderViewerURL":"\/vds\/viewer\/cat\/242?embed=1","mapURL":"\/vds\/map\/cat\/242","viewerURL":"\/vds\/viewer\/cat\/242","builderType":"","productType":"App\\Models\\CatalogBaseMolecular","geo_price":"212.00","geo_price_symbol":"$212.00","category":{"id":239,"categories":"Cas9 Vectors \u0026 Virus","pid":15,"url_key":"cas9-expression-vectors-and-viruses.html","css":null,"wid":0,"breadcrumbs":null,"breadcrumbsIdJson":"","breadcrumbsHtml":"","description":null,"meta_title":"Cas9 Vectors \u0026 Virus","meta_keywords":"Cas9 Vectors \u0026 Virus","meta_description":"Cas9 Vectors \u0026 Virus","deleted_at":null,"enable":"N","parent_list":"8,15","table_name":null,"image":null,"independentPage":0,"top_type":0,"sort_order":null,"in_footer":0,"fid":null,"created_at":"2024-12-20 01:58:15","updated_at":"2024-12-20 02:01:54"},"info":{"id":17913,"cat_no_base":"K203","parent_id":2723,"description":"\u003Cp\u003EdCas9-KRAB is used for CRISPR gene repression (CRISPRi). The Cas9 Double Mutant (dCas9) has changes at amino acid positions D10A and H840A which completely inactivate both the nuclease and nickase activities. In this construct, dCas9 carries a C-terminal Kr\u0026uuml;ppel associated box (KRAB) domain. By targeting dCas9-KRAB to a promoter region, users will be able to specifically repress expression of virtually any gene of interest. This dCas9-KRAB lentiviral vector may be used for either non-viral transfection, or packaged into lentivirus for stable integration of dCas9-KRAB into host cells. Use this dCas9-KRAB lentiviral vector in conjunction with a CRISPRi sgRNA lentiviral vector designed specifically for CRISPR repression.\u003C\/p\u003E","disclaimer":"\u003Ca href=\u0022\/terms#disclaimer-section\u0022\u003EClick for more info\u003C\/a\u003E","application":null,"components":null,"cas9_origin":null,"concentration":null,"enzymes_size":null,"genecraft_series":null,"guarantee":null,"population":null,"qc":null,"format_general":"Vector","including_screening_kit":null,"expression_system_general":null,"purity":null,"image":null,"insert_size":null,"shipping_conditions":"\u003Cp\u003EShipped at ambient temperature\u003C\/p\u003E","source_catalog_number":null,"inactivation_protocol":null,"led_viewer_compatibility":null,"unit_definition":null,"vector":"pLenti-EF1a-dCas9-KRAB","reaction_buffer":null,"storage_buffer":null,"caution":"This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.","storage_condition":null,"product_volume":null,"reporter":null,"safeview_series":null,"source_catno":null,"stain_color":null,"supplier":"ABM","internal_supplier":null,"internal_note":null,"inventory_location":"Chemical\/Vector Freezer- RACK-1","note":null,"recommend":null,"depositor":null,"licensor_name":null,"licensor_contact_information":null,"contract_termination_date":null,"royalty_rates":null,"cas_type":null,"cas_origin":null,"cas_protein_marker":null,"source":null,"endotoxin_level":null,"additional_information":null,"titer":null,"nucleotide_format":null,"protocol_overview":null,"source_price":null,"created_at":"2022-12-22 01:03:51","updated_at":"2025-03-28 18:24:43","short_description":"\u003Cp\u003EThis Cas9 Double Mutant (dCas9) carries a C-terminal Kr\u00fcppel associated box (KRAB) domain. By targeting dCas9-KRAB to a promoter region, users will be able to specifically repress expression of virtually any gene of interest.\u003C\/p\u003E","reaction_definition":null,"specificity":null,"promotions":null},"maps":[],"media":[],"gene":null}