dCas9-TET1CD Lentiviral Vector

Cat. No.
K096
Unit
10 µg
Price
$212.00
Cat. No. K096
Name dCas9-TET1CD Lentiviral Vector
Unit 10 µg
Description

This construct consists of the catalytic domain of Ten-Eleven Translocation dioxygenase 1 (TET1CD) fused to the C-terminus of Cas9 Double Mutant (dCas9). The Cas9 Double Mutant has changes at amino acid positions D10A and H840A which completely inactivate both nuclease and nickase activities; whereas the TET1 domain facilitates the process of demethylation leading to transcriptional up-regulation. By using specific sgRNAs, the dCas9-TET1CD can be targeted to a promoter region allowing for epigenetic control over the expression of almost any gene of interest.

Vector pLenti-EF1a-dCas9-tet1CD
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. K096
Print/Download Datasheet
Search CoA here
There are no Documents for this product yet!
There are no FAQs for this product yet!
There are no references for this product yet!
This product has no review yet.
Controls and Related Product:

CAT.NO
G2500
UNIT
1.0 ml
PRICE
$245.00

CAT.NO
LV053
UNIT
200µl
PRICE
$355.00

CAT.NO
G520
UNIT
10 reactions
PRICE
$99.00

CAT.NO
K048
UNIT
9.5µg (50pmol/ 50µL)
PRICE
$57.50

CAT.NO
G990
UNIT
100 Reactions
PRICE
$705.00

CAT.NO
G515
UNIT
1.0 ml
PRICE
$190.00