Recombinant Human Eotaxin (CCL11) (E. coli)

Cat. No.
Z100175
Unit
Price
$92.00
Cat. No. Z100175
Name Recombinant Human Eotaxin (CCL11) (E. coli)
Description Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.
Organism Human (H. sapiens)
Unit quantity 20 µg
Family Chemokine-beta Family (CC)
Aliases SCYA11
Gene Symbol CCL11
Gene ID 6356
Accession Number P51671
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 8.5 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from as 0.2 μm filtered solution in PBS (pH 7.5)
Function Activity was determined by the ability to induce chemotaxis of purified eosinophils at concentrations ranging between 50-100 ng/mL.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100175
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