Recombinant Human GGF2

Cat. No.
Z101655
Unit
Price
$920.00
Cat. No. Z101655
Name Recombinant Human GGF2
Description Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. The ErbB2 and ErbB4 receptors cooperate in transmission of neuregulin-1 signals in the heart, whereas ErbB2 and ErbB3 cooperate in neural crest cells.
Organism Human (H. sapiens)
Unit quantity 50 µg
Family Other Growth Factors/Cytokines
Aliases ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF
Gene Symbol GGF2
Gene ID 3084
Accession Number Q02297
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 34 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Formulation Recombinant GGF2 was lyophilized from a 0.2 μm filtered 0.02M PB, pH 7.0.
Function The ED(50) was determined by the dose-dependent phosphorylation of human MCF-7 cells was found to be < 20 ng/mL, corresponding to a specific activity of 5.0 x 10^4 Units/mg.
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z101655
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