Recombinant Human IFNA4 (E. coli)

Cat. No.
Z102405
Unit
Price
$92.00
Cat. No. Z102405
Name Recombinant Human IFNA4 (E. coli)
Description All known subtypes of IFN- alpha show the same antiviral antiparasitic, antiproliferative activities. IFN-alpha forms are produced by monocytes/macrophages, lymphoblastoid cells, fibroblasts, and a number of different cell types following induction by viruses, nucleic acids, glucocorticoid hormones, and low-molecular weight substances. All IFN-alpha subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. IFN-alpha and IFN-beta are thought to bind to the same receptor. Signal transduction mechanisms elicited after binding of IFN-alpha to its receptors involves tyrosine phosphorylation (see also: PTK; protein tyrosine kinase) of various non-receptor tyrosine kinases belonging to the Janus kinases.
Organism Human (H. sapiens)
Unit quantity 50 µg
Family IL-10/Interferon Family
Aliases IFN-alpha4a, INFA4
Gene Symbol IFNA4
Gene ID 3441
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 19.6 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Function The ED(50) was determined by the dose-dependent proliferation of KMS15 cells and was found to be <0.05ng/mL.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102405
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