SensiStain™ Anti-CMTM6 Antibody

Cat. No.
HY000275
Unit
0.1 ml
Price
$162.50
Cat. No. HY000275
Name SensiStain™ Anti-CMTM6 Antibody
Unit 0.1 ml
Clone IHC700
Category IHC Antibodies
Gene Name CMTM6
Gene Full Name CKLF-like MARVEL transmembrane domain containing 6
Alias FLJ20396
Accession Number BC002797
Application ELISA, IHC
Raised In Mouse
Clonality Monoclonal
Reactivity Human
Description

CMTM6, also referred to as CKLF Like MARVEL Transmembrane Domain Containing 6, is widely expressed in many tissues, but the function relatively remains unknown. SensiStain™ Anti- CMTM6 Antibody detects the presence of CMTM6 which can be found binding to PD-L1 and maintains its cell surface expression. Studies have showed that due to the binding to PD-L1, CMTM6 co-localizes at plasma membrane and recycling endosomes preventing PD-L1 from being targeted for lysosome-mediated degradation. Due to the high specificity CMTM6 has with PD-L1, it can be studied alongside with PD-L1 as it has a role in suppression of tumour-specific T cell activity.

Immunogen Recombinant Protein
Isotype IgG1
Uniprot Number Q9NX76
Storage Buffer Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage Condition

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing.

Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY000275
Print/Download Datasheet
Search CoA here
There are no Documents for this product yet!
There are no FAQs for this product yet!
  • Gao, F., Chen, J., Wang, J., Li, P., Wu, S., Wang, J., & Ji, Y. "CMTM6, the newly identified PD-L1 regulator, correlates with PD-L1 expression in lung cancers" Biochemistry and biophysics reports 20:100690 (2019).
This product has no review yet.