Lenti-HPV E6/E7 (Puro) Virus, High Titer

Cat. No.
LV617
Unit
2 x 100 µl
Price
$1,025.00
Cat. No. LV617
Name Lenti-HPV E6/E7 (Puro) Virus, High Titer
Unit 2 x 100 µl
Unpacking and Storage Instructions

Lentiviruses are shipped with dry ice. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles.

Description

High Titer (109 IU/ml) Recombinant 
Lentivirus expressing the HPV-16 E6/E7 gene.

Application

Cell immortalization of keratinocytes.

Expression System Type Lentivirus
Note

Not for resale without prior written consent of abm.

Caution

This product is distributed for laboratory 
research only. 

Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. LV617
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  • Balducci, L et al. "Immortalization of human adipose-derived stromal cells: production of cell lines with high growth rate, mesenchymal marker expression and capability to secrete high levels of angiogenic factors" Stem Cell Research & Therapy 3:63 (2014). DOI: 10.1186/scrt452. PubMed: 24887516. Application: Immortalization.
  • Calvo, F et al. "Isolation and Immortalization of Fibroblasts from Different Tumoral Stages" Bio-protocol 4(7):e1097 (2014). Application: Immortalization.
  • He, et al. "The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression" EMBO Molecular Medicine 11:1426-1449 (2015). DOI: 10.15252/emmm.201404976.
  • Coleman, S et al. "A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus" PLoS Pathog 12.7:e1005755 (2016). DOI: 10.1371/journal.ppat.1005755. Application: Immortalization.
  • Lee, Y., Berríos-Vázquez, G., Maes, R. K., Kiupel, M., Desmarets, L. M. B., Nauwynck, H. J., & Soboll Hussey, G. (2023). Development of immortalized feline respiratory epithelial cells in an air-liquid-interface culture system for feline herpesvirus-1 study. Virus Research, 326, 199063. https://doi.org/10.1016/j.virusres.2023.199064
  • He, C., Lv, X., Liu, J., Ruan, J., Chen, P., Huang, C., Angeletti, P. C., Hua, G., Moness, M. L., Shi, D., Dhar, A., Yang, S., Murphy, S., Montoute, I., Chen, X., Islam, K. N., George, S., Ince, T. A., Drapkin, R., … Wang, C. (2024). HPV-YAP1 oncogenic alliance drives malignant transformation of fallopian tube epithelial cells. EMBO Reports, 25(10), 4542–4569. https://doi.org/10.1038/s44319-024-00233-3
  • Huang, C., Lv, X., Chen, P., Liu, J., He, C., Chen, L., Wang, H., Moness, M. L., Dong, J., Rueda, B. R., Davis, J. S., & Wang, C. (2022). Human papillomavirus targets the YAP1-LATS2 feedback loop to drive cervical cancer development. Oncogene, 41(30), 3761–3777. https://doi.org/10.1038/s41388-022-02390-y
  • Jenkins, L., Jungwirth, U., Avgustinova, A., Iravani, M., Mills, A., Haider, S., Harper, J., & Isacke, C. M. (2022). Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade. Cancer Research, 82(16), 2904–2917. https://doi.org/10.1158/0008-5472.can-21-4141
  • Choi, K. Y., El-Hamdi, N., & McGregor, A. (2022). Endothelial Cell Infection by Guinea Pig Cytomegalovirus Is a Lytic or Persistent Infection Depending on Tissue Origin but Requires Viral Pentamer Complex and pp65 Tegument Protein. Journal of Virology, 96(17), e00831-22. https://doi.org/10.1128/jvi.00831-22
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