SensiStain™ Anti-B7-H4 Antibody

Cat. No.
HY000305
Unit
0.1 ml
Price
$273.00
Cat. No. HY000305
Name SensiStain™ Anti-B7-H4 Antibody
Unit 0.1 ml
Clone IHC104
Category IHC Antibodies
Gene Name B7-H4
Application ELISA,IHC
Raised In Mouse
Clonality Monoclonal
Reactivity Human
Description

B7-H4 is a glycosylated transmembrane protein of the B7 family. It binds to activated T cells to moderate the T cell responses via cell cycle arrest in the T cell. Reverse signaling can induce either cell cycle arrest or apoptosis in the B7-H4 expressing cell. B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status.

Immunogen Recombinant Protein
Isotype IgG2b
Uniprot Number Q7Z7D3
Storage Buffer Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage Condition

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing.

Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY000305
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